Hydroxychloroquine Impurity 19 - Names and Identifiers
Hydroxychloroquine Impurity 19 - Physico-chemical Properties
Molecular Formula | C9H4Cl3N
|
Molar Mass | 232.49 |
Density | 1.523±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 106 - 108°C |
Boling Point | 326.7°C at 760 mmHg |
Flash Point | 181.2°C |
Solubility | Chloroform (Sparingly), Toluene (Slightly, Sonicated) |
Vapor Presure | 0.000405mmHg at 25°C |
Appearance | Solid |
Color | Pale Beige to Brown |
Storage Condition | 2-8°C |
Refractive Index | 1.667 |
Hydroxychloroquine Impurity 19 - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | R25 - Toxic if swallowed
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
Hydroxychloroquine Impurity 19 - Introduction
4,5, 7-tricholoro Quinoline is an organic compound with the molecular formula C9H4Cl3N, which is a colorless crystalline solid. The following is a description of the nature, use, preparation and safety information of 4,5, 7-tricloro Quinoline:
Nature:
-Appearance: 4,5, 7-tricloro Quinoline exists in the form of white to yellow crystals.
-Melting point: Its melting point is 121-123 ° C.
-Boiling point: The vapor pressure is low, so its boiling point is higher.
-Solubility: 4,5, 7-tricloro Quinoline is soluble in organic solvents such as alcohols and ketones.
Use:
-Chemical research: 4,5, 7-tricloro Quinoline is commonly used as a reagent in organic synthesis and coordination chemistry research.
-Agriculture: It is also used as an intermediate for certain pesticides and insecticides.
Method:
4,5, 7-tricholoro Quinoline can be prepared by the following methods:
-hydrogen peroxide oxidation method: 2-aminopyridine is reacted with hydrogen peroxide to generate 3,4, 5-trichloropyridine. Subsequently, 3,4, 5-trichloropyridine was converted to 4,5, 7-trichlororo Quinoline by nitric acid oxidation.
Safety Information:
- 4,5, 7-trichlororo Quinoline has not yet fully understood the potential hazards to the human body, so care should be taken when using it.
-Exposure to 4,5, 7-tricholoro Quinoline may cause skin irritation and eye irritation, direct contact should be avoided.
-When using or handling 4,5, 7-tricloro Quinoline, take appropriate protective measures, such as wearing protective glasses, gloves and suitable protective clothing.
-When storing 4,5, 7-tricloro Quinoline, keep it in a sealed container and keep it away from open flames and high temperature environments.
Last Update:2024-04-10 22:29:15